Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep174 | Endocrine tumours and neoplasia | ECE2017

Jejunum/ ileum Neuroendocrine Tumours: results of a multicentric retrospective study

Marques Ana Paula , Santos Ana Paula , Claro Isabel , Sanches Ana Cristina , Fernandes Isabel , Lopes Jose Manuel , Preto John , Rodrigues Fernando , Catarino Ana Luisa , Mellidez Juan , Pereira Bernardo , Rocha Gustavo , Bugalho Maria Joao , Neuroendocrinos Grupo Estudos Tumores

Introduction: The Neuroendocrine Tumors Study Group of the Portuguese Endocrine Society (SPEDM) performed the first observational study between November 2012 and July 2014 too assess the profile of Gastroenteropancreatic Neuroendocrine Tumours (GEP-NET) patients (pts) followed at the main Portuguese hospitals. Several demographic and clinical data were collectedObjective: Characterize the clinicopathological features and treatment of patients with NET or...

ea0040oc4 | (1) | ESEBEC2016

TERT promoter mutations in pancreatic endocrine tumours are frequent in tumours from patients with hereditary syndromes

Vinagre Joao , Nabais Joana , Pinheiro Jorge , Batista Rui , Oliveira Rui , Goncalves Pedro , Pestana Ana , Reis Marta , Mesquita Barbara , Pinto Vasco , Lyra Joana , Godinho Miguel , Lopes Jose Manuel , Sobrinho-Simoes Manuel , Soares Paula

Objective: One of the hallmarks of cancer is its unlimited replicative potential. Recently, telomerase promoter (TERTp) mutations were presented as novel mechanism for telomerase re-activation/expression. Due to this fact, it was our objective to study pancreatic endocrine tumours (PET) and related cell lines, to determine if TERTp mutations were present.Design: We performed characterization of the TERTp in a series of 55 PETs and three common PET cell l...